N8 Lysosomal dysfunction in glia (Zunke)
The role of lysosomal dysfunction within glial cells in Parkinson’s disease
Term: 16.02.2021 – 15.11.2024
Recent studies suggest that glial dysfunction significantly contributes to neurodegeneration in Parkinson’s disease (PD). Since lysosomal degradation is important for glial cell function, we aim to analyse the molecular consequences of lysosomal dysfunction within different glial cell lines. A better understanding of glial regulation and lysosomal turnover will help to unravel molecular mechanisms in PD and might facilitate the identification of novel therapeutic strategies in PD.
